Naomi Watts

as Iris

Bill Murray

as Walter

Ann Dowd

as Marjorie

Constance Wu

as Tuesday

Sarah Pidgeon

as Val

Carla Gugino

as Elaine

Noma Dumezweni

as Barbara

Felix Solis

as Hektor

Owen Teague

as Carter

Bing

as Apollo

Gina Costigan

as Jocelyn

Josh Pais

as Jerry

Cloé Xhauflaire

as Camille

Susan Wands

as Female Dinner Guest

Susan Lynskey

as Host

Joel Van Liew

as Male Dinner Guest

Annie Fox

as Jenna

Carrie Vu

as Viv

Sue Jean Kim

as Blossom

Joe Castle Baker

as Young Professor

Gary Littman

as Grant

Sarah Baskin

as Mara

Jess Gabor

as Stella

Anna Fikhman

as Nosy Neighbor

Bruce Norris

as Dr. Novak

Amy Warren

as Pantsuit Woman

Gabe Castillo

as Security Guard

Juliet Brett

as Sophie

Afsheen Misaghi

as Shervin

Seth Barrish

as Harry

Ian Lithgow

as Larry

Jonathan Raviv

as Party Goer

Matt Leisy

as Dog Owner

Myrna Cabello

as Lydia

Tom McCarthy

as Dr. Warren

Gregory Abbey

as Robert

John Leone

as Conductor

Cedric Cannon

as Chess Player (uncredited)

Grayson Powell

as Bearded Writer (uncredited)

Alex Ziwak

as New YOrk Rangers Fan (uncredited)