William Powell

as Nick Charles

Myrna Loy

as Nora Charles

Lucile Watson

as Mrs. Marta Charles

Gloria DeHaven

as Laura Belle Ronson

Anne Revere

as Crazy Mary

Helen Vinson

as Helena Draque

Harry Davenport

as Dr. Bertram Charles

Leon Ames

as Edgar Draque

Donald Meek

as Willie Crump

Edward Brophy

as Brogan

Lloyd Corrigan

as Dr. Bruce Clayworth

Anita Sharp-Bolster

as Hilda

Ralph Brooke

as Peter Berton

Donald MacBride

as Police Chief MacGregor

Morris Ankrum

as Willoughby Peavy

Nora Cecil

as Miss Peavy

Minor Watson

as Sam Ronson

Irving Bacon

as Tom

Virginia Sale

as Tom's Wife

Asta Jr.

as Asta

Joseph Crehan

as Clancy - Policeman at Railroad Station (uncredited)

Tom Dugan

as Studs Lonnegan (uncredited)

Wally Cassell

as Bill Burns (uncredited)

Edward Gargan

as Mickey Finnegan (uncredited)

Rex Evans

as Fat Man in Train Passageway (uncredited)

Charles Halton

as R.T. Tatum (uncredited)

Paul Langton

as Tom Clayworth (uncredited)

Etta McDaniel

as Ronson's Maid (uncredited)

Clarence Muse

as Porter on Train (uncredited)

Robert Emmett O'Connor

as Baggage Attendant on Train (uncredited)

Garry Owen

as Pool Player (uncredited)

Jack Perry

as Man in Pool Hall Brawl (uncredited)

William H. O'Brien

as Train Passenger (uncredited)

Oliver Blake

as Reporter (uncredited)

Tom Fadden

as Train Passenger in Passageway (uncredited)

Sam Flint

as Hotel Clerk (uncredited)

Harry Hayden

as Train Conductor (uncredited)

Mitchell Lewis

as Third Man Outside Barber Shop(uncredited)