David Wenham

as Damien

Jan Decleir

as Bishop Köckerman

Kate Ceberano

as Princess Liliuokalani

Sam Neill

as Prime Minister Gibson

Derek Jacobi

as Father Leonor Fousnel

Alice Krige

as Mother Marianne

Kris Kristofferson

as Rudolph Meyer

Leo McKern

as Bishop Maigret

Peter O'Toole

as William Williamson

Tom Wilkinson

as Brother Dutton

Aden Young

as Dr. Kalewis

Chris Haywood

as Clayton Strawn

George O'Hanlon, Jr.

as Evans

Thom Hoffman

as Dr. William Saxe

Michaël Pas

as Dr. Stottard

Dirk Roofthooft

as Father Conrardy