John Candy

as Frank Dooley

Eugene Levy

as Norman Kane

Robert Loggia

as Michael Carlino

Kenneth McMillan

as Captain Clarence O'Connell

Meg Ryan

as Maggie Cavanaugh

Brion James

as Anthony Lazarus

Jonathan Banks

as Clyde Klepper

Don Stroud

as Sergeant Rizzo

Larry Hankin

as Kokolovitch

Steve Railsback

as The Cowboy

Robert Burgos

as Mel Nedler

Tony Burton

as Cappy

Robert Gray

as Butcher

Larry Jenkins

as Raisin

Stacy Keach, Sr.

as Judge

Bruce Kirby

as Police Captain

Savely Kramarov

as Olaf

Judy Landers

as Noreen

Tommy Lister Jr.

as Bruno

James Tolkan

as Lou Brackman

K.C. Winkler

as Vicki

Glenn Withrow

as Larry Lupik

David Wohl

as Prosecutor

Melanie Gaffin

as Little Girl

Ira Miller

as 1st Toxic Guard

Royce D. Applegate

as 2nd Toxic Guard

John Solari

as Dolan

David Hess

as Gunman #4

Christine Dupree

as Peep Show Girl

Nicholas Worth

as Transvestite

Sylvia Kauders

as Older Woman at Party

Wilson Camp

as Older Man at Party

Edith Fields

as Party Guest

J. Jay Saunders

as Mayor

Tito Puente

as Band Leader

Rick Avery

as Cobb

Joe Seely

as Kid

Mark Carlton

as Court Clerk

Teagan Clive

as Staff Member