John Michael Higgins

as David Letterman

Daniel Roebuck

as Jay Leno

Kathy Bates

as Helen Kushnick

Bob Balaban

as Warren Littlefield

Ed Begley Jr.

as Rod Perth

Peter Jurasik

as Howard Stringer

Reni Santoni

as John Agoglia

John Kapelos

as Robert Morton

Steven Gilborn

as Peter Lassally

John Getz

as Brandon Tartikoff

Lawrence Pressman

as Bob Wright

Sandra Bernhard

as Sandra Bernhard

Treat Williams

as Michael Ovitz

David Brisbin

as Alan Levine

Michael Chieffo

as Rick Ludwin

Wendy Cutler

as Reporter #2 Letterman Press Conference

Nancy Cheryll Davis

as Reporter #2 Carnegie Hall

Paul Elder

as Rupert Murdoch

Michael Fairman

as Michael Gartner

John R. Fors

as Writer #2

Nicholas Guest

as Robert Iger

Lucinda Jenney

as Debbie Vickers

Ivan Kane

as Reporter #1

Ken Kragen

as Ken Kragen

Susan Krebs

as Airport Attendant

James Kiriyama-Lem

as Reporter #1 Letterman Press Conference

Dan Lipe

as Writer #1

Aaron Lustig

as Paul Shaffer

Cynthia Lynch

as Laurie Diamond

Michael C. McCarthy

as Jim Brogan

Kerry Noonan

as Letterman's Girlfriend

Penny Peyser

as Susan Binford

Little Richard

as Little Richard

Ann Ryerson

as Betty Hudson

Kevin Scannell

as Dick Ebersol

Edmund L. Shaff

as Jack Welsh

Joanne Takahashi

as Thai Waitress

Arthur Taxier

as Lee Gabler

Cathy Worthington

as Kragen's Asst.

Rich Little

as Johnny Carson

Arnold F. Turner

as Reporter #3 Letterman Press Conference

Dean Francois

as CBS Executive to Howard Stringer (uncredited)

Angie Gray

as Mrs. Wright (uncredited)