Wesley Snipes

as Blade

Kris Kristofferson

as Whistler

Ron Perlman

as Reinhardt

Leonor Varela

as Nyssa

Norman Reedus

as Scud

Thomas Kretschmann

as Damaskinos

Luke Goss

as Nomak

Matt Schulze

as Chupa

Danny John-Jules

as Asad

Donnie Yen

as Snowman

Karel Roden

as Kounen

Marit Velle Kile

as Verlaine

Tony Curran

as Priest

Daz Crawford

as Lighthammer

Santiago Segura

as Rush

Samuel Le

as Jigsaw

Marek Vašut

as Golem

Pete Lee-Wilson

as Blood Bank Doctor / Reaper

Paul Kasey

as Blood Bank Guard / Reaper

Andrea Miltner

as Blood Bank Nurse

Ladislav Beran

as Drug Dealer

Jiří Maria Sieber

as Blood Bank Guard

Bridge Markland

as Vampire with Exposed Spine

Jamie Wilson

as Reaper

Stuart Luis

as Reaper

Ladislav Mohyla

as Reaper

Jan Malík

as Reaper

Jan Révai

as Reaper

Mário Wild

as Reaper

Tomáš Böhm

as Reaper

Zdenek Bubák

as Reaper

Jan Loukota

as Reaper

Jan Bursa

as Reaper

Petr Krusalnicky

as Reaper

Jaroslav Misek

as Reaper

Karel Vávrovec

as St. Cloud

Jaroslav Peterka

as Choad

Miloš Kulhavý

as Little G

Ivan Mareš

as Tea Bag

Lennox Brown

as Man in London Porno Shop

André Hyde-Braithwaite

as Young Blade

Pavel Cajzl

as Moscow Vampire (uncredited)

Olga Lounová

as Prostitute (uncredited)

Stephen R. Peluso

as Paramedic (uncredited)

John Salvitti

as Moscow Vampire Attacking Blade (uncredited)

Kenji Tanigaki

as Moscow Vampire Attacking Blade (uncredited)

Michael Woods

as Moscow Vampire Attacking Blade (uncredited)