Anna Faris

as Cindy Campbell

Regina Hall

as Brenda Meeks

Craig Bierko

as Tom Ryan

Bill Pullman

as Henry Hale

Anthony Anderson

as Mahalik

Leslie Nielsen

as President Baxter Harris

Molly Shannon

as Marilyn

Michael Madsen

as Oliver

Chris Elliott

as Ezekiel

Carmen Electra

as Holly

Shaquille O'Neal

as Shaq

Phil McGraw

as Dr. Phil

Cloris Leachman

as Mrs. Norris

Conchita Campbell

as Rachel

Beau Mirchoff

as Robbie Ryan

Kevin Hart

as CJ

DeRay Davis

as Marvin

Simon Rex

as George

YoungBloodZ

as YoungBloodZ

Bryan Callen

as Harper

Alonzo Bodden

as Jamison

Dave Attell

as Knifeman

Holly Madison

as Blonde #1

Bridget Marquardt

as Blonde #2

Kendra Wilkinson

as Blonde #3

Drew Mikuska

as Cody

Chingy

as Chingy

Fabolous

as Gunman

Lil Jon

as Gloating Driver

Henry Mah

as Mr. Koji

Garrett Masuda

as Japanese Ghost Boy

John Reardon

as Jeremiah

Campbell Lane

as Amos

Catherine Barroll

as Female Elder #1

Anna Ferguson

as Female Elder #2

Sean Allan

as Male Elder #2

Ralph Alderman

as Male Elder #3

Brad Sihvon

as 'His Brother, The Sheriff!'

Dave Leach

as Mordecai

Andrew McNee

as Hoss

Tomoko Sato

as Japanese Ghost Woman

Edward Moss

as Michael Jackson

Dru Williams

as Cindy's Husband

Debra Wilson

as Oprah

Laura Dash

as Saw Villain - Alien

David Mylrea

as Zoltar / 'I'll Pay You'

Craig Mazin

as Saw Villain (voice)

David Zucker

as Zoltar (voice)

Michael McDonald

as Tiffany Stone

Champagne Powell

as Don King

Steve Archer

as Secret Service Agent

Tim Henry

as Dock Foreman

Alex Bruhanski

as Tiffany's Trainer

Doug Abrahams

as Fight Referee

Blaine Anderson

as Vendor at Fight

Dale Wolfe

as Hang Gliding Man

Ann Warn Pegg

as 'Were You Naked?'

Jess McLeod

as Little Girl

David MacKay

as 'Alien Attack!'

Tony Ali

as Terrorist

Jana Mitsoula

as Running Woman #1

Sharon Simms

as Running Woman #2

Mark Burgess

as 'My Bowels Have Stopped Moving!'

Wes Taylor

as Marilyn's New Husband

Gwenda Lorenzetti

as Mr. Koji's Assistant

Brenda McDonald

as Old Lady Henderson

Tim O'Halloran

as Pigface Joe

Darren Rizzolo

as Spit Take Kid #1

Adam Cannel

as Spit Take Kid #2

Sadie Decoste

as Spit Take Kid #3

Michelle Grigor

as Spit Take Kid #4

Leandro Iddrisu

as Spit Take Kid #5

Justin Callan

as Spit Take Kid #6

Yan-Kay Crystal Lowe

as Chingy's Girl #1

Christie Laing

as Chingy's Girl #2

Angelique Naude

as Chingy's Really Hot Waitress

Dexter Bell

as Chingy's Hype Man

Beverley Breuer

as Blonde Woman in Alien Basket

Scott Barratt

as Fight Announcer

Barry W. Levy

as National Spokesman

Darryl Scheelar

as Shotgun Man

Rorelee Tio

as Yoko

Steve Kiziak

as Tom's Neighbor #1

Link Baker

as Tom's Neighbor #2

Kimberley Buchanan

as Tom's Neighbor #3

Kathryn Dobbs

as School Teacher

Tony Morelli

as Ball Scratcher

Tina Hosford

as Wet T-Shirt Girl #1

Elisa King

as Wet T-Shirt Girl #2

Andrea Morrow

as Wet T-Shirt Girl #3

Monica Dillon

as Mahalik's Grandmother

Sarah Edmondson

as Bar Waitress

Kwesi Ameyaw

as Soldier

Ted Friend

as Reporter

Daniel Bruce

as Belgian Minister

Chic Gibson

as UN Diplomat #1

Robbie Segulam

as UN Diplomat #2

Nimet Kanji

as UN Diplomat #3

Gabriela Cerecero

as UN Diplomat #4

Michael Ikeda

as UN Diplomat #5

Mina E. Mina

as UN Diplomat #6

Ahmad Sharmrou

as UN Diplomat #7

Steadwick D'Penha

as UN Diplomat #8

Gregory Bennett

as Russian Diplomat

Uget Ebony

as UN Diplomat #10

George Grove

as Doctor

Charlie Sheen

as Tom Logan (uncredited)

James Earl Jones

as Narrator (uncredited)

Patrice O'Neal

as Rasheed (uncredited)

Chris Williams

as Marcus (uncredited)

Mashiah Vaughn-Hulbert

as Principal (uncredited)

Kimani Ray Smith

as Cut Man (uncredited)

Yaroslav Poverlo

as Belgian Representative in UN (uncredited)

Amber Borycki

as Dancer (uncredited)