Margot Robbie

as Harley Quinn

Rosie Perez

as Renee Montoya

Mary Elizabeth Winstead

as Helena Bertinelli / Huntress

Jurnee Smollett

as Dinah Lance / Black Canary

Ewan McGregor

as Roman Sionis

Ella Jay Basco

as Cassandra Cain

Chris Messina

as Victor Zsasz

Ali Wong

as Ellen Yee

David Ury

as Sleazy Breeder

Sara Montez

as Shallow Friend #1 / Kathrine

Izabel Pakzad

as Shallow Friend #2

Daniel Bernhardt

as Sionis' Chauffeur

Kc Strubbe

as Naïve Teammate

Jacky Shu

as Skeptical Teammate

Paloma Esparza Rabinov

as Bitchy Teammate

Derek Wilson

as Detective Tim Munroe

Joe Bucaro III

as Carlos Rossi

James Henry Williams Jr.

as Ace Chemical Police Officer

François Chau

as Mr. Keo

Miyuki Matsunaga

as Mrs. Keo

Anna Mikami

as Miss Keo (16 yrs)

Bruno Oliver

as Bodega Cook (Sal)

Keisha Tucker

as Roller Derby Girl

Matthew Willig

as Happy

Jeremy Denzlinger

as Desk Sergeant

Michael Masini

as Officer Drago

Charles Carpenter

as Processing Officer

Daniel Cole

as Patrol Cop

Jesse Bush

as Patrol Cop

Steven Williams

as Captain Patrick Erickson

Charlene Amoia

as Maria Bertinelli

Paul Lasa

as Helena's Father

Ella Mika

as Young Helena

Robert Catrini

as Stefano Galante

Eddie Alfano

as Helena's Bodyguard

Chris Carnel

as Desk Sergeant

Buddy Sosthand

as Coffee Cup Cop

Tim Sitarz

as Donut Cop

Shawn Balentine

as Key Card Cop

Shahaub Roudbari

as Smarmy Guy

Pramod Kumar

as Irate Shopkeeper

Christine Engh

as Elderly Woman

K.K. Barrett

as Dr. Aguilar

David Bianchi

as Sionis Henchman #1

Simon Rhee

as Cell Guard

Terrence Julien

as Cell Guard

George Crayton

as Prisoner

Caleb Spillyards

as Prisoner

Qiang Li

as Prisoner

Anthony N.

as Prisoner

Sala Baker

as Prisoner

Christian Womack

as Prisoner

Bryan Sloyer

as Prisoner

Kofi Yiadom

as Mercenary

Efka Kvaraciejus

as Mercenary

Sam Hargrave

as Mercenary

Dennis Keiffer

as Mercenary

Dana Lee

as Doc

Bojana Novaković

as Erika

Andy Hoff

as Erika's Date

Eric Michael Cole

as Disgruntled Man

Oakley Lehman

as Mercedes Gang

Richard King

as Mercedes Gang

Tim Rigby

as RR Passenger

Judy Kain

as Bespectacled Secretary (uncredited)

Rj Wayne

as Tough Guy (uncredited)

Zack Whyel

as Roman's Healer (uncredited)

Ellay Watson

as Roller Derby Fan (uncredited)

Karen Teliha

as Nun (uncredited)

Nev Smith

as Gotham Detective (uncredited)

Greice Santo

as Scantily Clad Crystal (uncredited)

Zeus Sagittarius

as Roman's Goon (uncredited)

Talon Reid

as Roman's Goon (uncredited)

Matthew Parry-Jones

as Club Goer (uncredited)

Brian Nuesi

as Husband (uncredited)

Adinett Nsabimana

as Girl at the Bar (uncredited)

Brandon Garic Notch

as Roman's Lift Goon (uncredited)

Anthony Molinari

as Mafiosi (uncredited)

Ego Mikitas

as Don (uncredited)

Lenora May

as Mrs. Marcucci (uncredited)

Jeff Lipary

as BBB Gang Member (uncredited)

Brandon Irvin

as Roman's Goon (uncredited)

Damon Hoffman

as Bodybuilder (uncredited)

William Guirola

as Thug (uncredited)

Nico Greetham

as Young Goon (uncredited)

Luis Richard Gomez

as Harley Super Fan (uncredited)

Shad Gaspard

as Lords Leader (uncredited)

Julian Garcia

as Roman's Goon (uncredited)

Eddie J. Fernandez

as Gauntlet Cop (uncredited)

Mike Ferguson

as Lord of the Avenue (uncredited)

Gerald Downey

as Judge (uncredited)

Jack Dourakos

as Club Goer (uncredited)

Sadyr Diouf

as Roman's Goon (uncredited)

Joey Courteau

as Club Dancer (uncredited)

Dan Cole

as Officer Timm (uncredited)

Lucas Di Medio

as Roman's Bodyguard (uncredited)

Jason Catron

as Sprang Bridge Soldier (uncredited)

David Anthony Buglione

as Joe Bertinelli (uncredited)