Johnny Depp

as Fred Abberline

Heather Graham

as Mary Kelly

Ian Holm

as Sir William Gull

Robbie Coltrane

as Peter Godley

Ian Richardson

as Sir Charles Warren

Jason Flemyng

as Netley

Katrin Cartlidge

as Dark Annie Chapman

Terence Harvey

as Ben Kidney

Susan Lynch

as Liz Stride

Paul Rhys

as Dr. Ferral

Lesley Sharp

as Kate Eddowes

Estelle Skornik

as Ada

Nicholas McGaughey

as Officer Bolt

Annabelle Apsion

as Polly

Joanna Page

as Ann Crook

Mark Dexter

as Albert Sickert / Prince Edward Albert Victor

Danny Midwinter

as Constable Withers

Samantha Spiro

as Martha Tabram

David Schofield

as McQueen

Bryon Fear

as Robert Best

Peter Eyre

as Lord Hallsham

Cliff Parisi

as Mac Bartender

Sophia Myles

as Victoria Abberline

Ralph Ineson

as Gordie

Amy Huck

as Gull's Maid

Rupert Farley

as Doss Landlord

Donald Douglas

as Hospital Director

John Owens

as Marylebone Governor

Liz Moscrop

as Queen Victoria

Ian McNeice

as Robert Drudge

Steve John Shepherd

as Special Branch Constable

Al Hunter Ashton

as Stonecutter

Poppy Rogers

as Alice Crook

Bruce Byron

as Ann Crook's Father

Melanie Hill

as Ann Crook's Mother

Andy Linden

as Carpenter

David Fisher

as Carpenter / Letter Writer

Gary Powell

as Constable #1

Steve Chaplin

as Constable #2

Vincent Franklin

as George Lusk

Louise Atkins

as Bold Hooker

Anthony Parker

as John Merrick

James Greene

as Masonic Governor

Dominic Cooper

as Constable #3

Carey Thring

as Police Photographer

Vladimír Kulhavý

as Rag & Bone Man

Graham Kent

as Records Clerk

Rupert Holliday-Evans

as Sailor

Simon Harrison

as Thomas Bond

Paul Moody

as Young Doctor

Glen Berry

as Young Labourer

Charles Parish

as Labourer #2

Gerry Grenn

as Funeral Minister / Letter Writer