Matt Damon

as Spirit (voice)

James Cromwell

as The Colonel (voice)

Daniel Studi

as Little Creek (voice)

Chopper Bernet

as Sgt. Adams (voice)

Jeff LeBeau

as Murphy / Railroad Foreman (voice)

John Rubano

as Soldier (voice)

Richard McGonagle

as Bill (voice)

Matt Levin

as Joe (voice)

Adam Paul

as Pete (voice)

Robert Cait

as Jake (voice)

Charles Napier

as Roy (voice)

Meredith Wells

as Little Indian Girl (voice)

Zahn McClarnon

as Little Creek's Friend (voice)

Michael Horse

as Little Creek's Friend (voice)

Donald Fullilove

as Train Pull Foreman (voice)